Older adults with newly diagnosed high-risk/secondary AML who achieved remission with CPX-351: phase 3 post hoc analyses.

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Financial Disclosure Statement

D.A.R. served as a consultant for AbbVie, Novartis, Pfizer, Spectrum, and Teva; and served on speaker bureaus for Gilead, Incyte, Jazz Pharmaceuticals, Millennium, and Seattle Genetics. D.H.R. holds stock ownership in AbbVie and patents/royalties with the University of Rochester. G.J.S. received research funding from AbbVie, Agios, Actinium, Amgen, Ariad, Astellas Pharma, Bristol Myers Squibb, Constellation, Cyclacel, Daiichi Sankyo, Deciphera, Delta-Fly, Forma, Fujifilm, Gamida, Genentech-Roche, Geron, Incyte, Jazz Pharmaceuticals, Karyopharm, Kite Pharma, Mateon, MedImmune, Novartis, Onconova, Pfizer, REGiMMUNE, Samus, Sangamo, Tolero, and Trovagene; served as a consultant for Agios, Amgen, AstraZeneca, Incyte, Novartis, and Ono Pharma; served on speakers bureaus for Agios, Amgen, Celgene, Gilead, Incyte, Sanofi, and Stemline; provided expert testimony for Kaiser Permanente; and holds stock in Amgen, Bristol Myers Squibb, Johnson & Johnson, and Pfizer. J.E.K. received honoraria from Gilead, Magellan, and Novartis; served as a consultant for Gilead, Magellan, Novartis, Pharmacyclics, and Seattle Genetics; received research funding from Boehringer Ingelheim, Cantex, Erytech, and Millennium; and received travel support from Gilead, Novartis, and Seattle Genetics. G.L.U. served as a consultant for Jazz Pharmaceuticals and Genentech and received honoraria from Astellas Pharma. M.J.W. received research funding from Amgen, Leadiant, Merck, and Shire; participated in advisory committees for Daiichi Sankyo; and holds stock ownership in Reata Pharmaceuticals. R.J.R. and S.F. are employees of and hold stock ownership/options in Jazz Pharmaceuticals. J.E.C. served as a consultant for Astellas Pharma, Daiichi Sankyo, Jazz Pharmaceuticals, Novartis, and Pfizer; and received research funding from Arog, Astellas Pharma, Daiichi Sankyo, Jazz Pharmaceuticals, Novartis, and Pfizer. J.E.L. served as a consultant for Agios, Daiichi Sankyo, Jazz Pharmaceuticals, and Pfizer. The remaining authors declare no competing financial interests.

Detailed information on funding amounts received by the authors of this publication is available at http://www.cms.gov/openpayments.

INDICATION

VYXEOS^® (daunorubicin and cytarabine) liposome for injection 44 mg/100 mg is indicated for the treatment of newly-diagnosed therapy-related acute myeloid leukemia (t-AML) or AML with myelodysplasia-related changes (AML-MRC) in adults and pediatric patients 1 year and older.